218269-34-2 , Carboxymethyl-b-cyclodextrin

218269-34-2 , Carboxymethyl-b-cyclodextrin
C56H84O49 / 1541.24

Carboxymethyl-b-cyclodextrin

Carboxymethyl-β-cyclodextrin is a cationic cyclodextrin that is used as a carrier for drugs. It has been shown to be able to bind nonsteroidal anti-inflammatory drugs (NSAIDs) with high affinity and selectivity. Carboxymethyl-β-cyclodextrin has also been shown to have a high stability in human serum and urine, as well as redox potentials that are close to physiological conditions. In addition, it can be easily detected by titration calorimetry and antibody binding assays. Carboxymethyl-β-cyclodextrin has been used in pharmaceutical preparations, including monoclonal antibody production and wastewater treatment.

CAS Number	218269-34-2
Product Name	Carboxymethyl-beta-cyclodextrin
IUPAC Name	2-[[(1R,3R,5R,6S,8R,10R,11S,13R,15R,16S,18R,20R,21R,23R,25R,26R,28R,30R,31R,33R,35R,36R,37R,38R,39R,40R,41R,42R,43R,44R,45R,46R,47R,48R,49R)-36,38,40,42-tetrakis(carboxymethoxy)-10,15-bis(carboxymethoxymethyl)-37,39,41,43,44,45,46,47,48,49-decahydroxy-20,25,30,35-tetrakis(hydroxymethyl)-2,4,7,9,12,14,17,19,22,24,27,29,32,34-tetradecaoxaoctacyclo[31.2.2.23,6.28,11.213,16.218,21.223,26.228,31]nonatetracontan-5-yl]methoxy]acetic acid
Molecular Formula	C56H84O49
Molecular Weight	1541.239
InChI	InChI=1S/C56H84O49/c57-1-15-42-47(89-12-26(69)70)36(82)54(93-15)104-44-17(3-59)95-56(38(84)49(44)91-14-28(73)74)105-45-18(4-60)94-55(37(83)48(45)90-13-27(71)72)103-43-16(2-58)92-53(35(81)46(43)88-11-25(67)68)101-41-21(7-87-10-24(65)66)97-51(33(79)30(41)76)99-39-19(5-85-8-22(61)62)96-50(32(78)29(39)75)100-40-20(6-86-9-23(63)64)98-52(102-42)34(80)31(40)77/h15-21,29-60,75-84H,1-14H2,(H,61,62)(H,63,64)(H,65,66)(H,67,68)(H,69,70)(H,71,72)(H,73,74)/t15-,16-,17-,18-,19-,20-,21-,29-,30-,31-,32-,33-,34-,35-,36-,37-,38-,39-,40-,41-,42-,43-,44-,45-,46-,47-,48-,49-,50-,51-,52-,53-,54-,55-,56-/m1/s1
InChI Key	CUJVBAPGYBSBHJ-YWBSARSQSA-N
SMILES	C(C1C2C(C(C(O1)OC3C(OC(C(C3OCC(=O)O)O)OC4C(OC(C(C4OCC(=O)O)O)OC5C(OC(C(C5OCC(=O)O)O)OC6C(OC(C(C6O)O)OC7C(OC(C(C7O)O)OC8C(OC(O2)C(C8O)O)COCC(=O)O)COCC(=O)O)COCC(=O)O)CO)CO)CO)O)OCC(=O)O)O